MX1

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MX1
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
AliasesMX1, IFI-78K, IFI78, MX, MxA, MX dynamin like GTPase 1
External IDsOMIM: 147150 HomoloGene: 1844 GeneCards: MX1
Gene location (Human)
Chromosome 21 (human)
Chr.Chromosome 21 (human)[1]
Chromosome 21 (human)
Genomic location for MX1
Genomic location for MX1
Band21q22.3Start41,420,304 bp[1]
End41,459,214 bp[1]
RNA expression pattern
PBB GE MX1 202086 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001144925
NM_001178046
NM_001282920
NM_002462

n/a

RefSeq (protein)

NP_001138397
NP_001171517
NP_001269849
NP_002453

n/a

Location (UCSC)Chr 21: 41.42 – 41.46 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Interferon-induced GTP-binding protein Mx1 is a protein that in humans is encoded by the MX1 gene.[3][4]

In mouse, the interferon-inducible Mx protein is responsible for a specific antiviral state against influenza virus infection. The protein encoded by this gene is similar to the mouse protein as determined by its antigenic relatedness, induction conditions, physicochemical properties, and amino acid analysis. This cytoplasmic protein is a member of both the dynamin family and the family of large GTPases.[4]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000157601 - Ensembl, May 2017
  2. ^ "Human PubMed Reference:".
  3. ^ Haller O, Staeheli P, Kochs G (Jul 2007). "Interferon-induced Mx proteins in antiviral host defense". Biochimie. 89 (6–7): 812–8. doi:10.1016/j.biochi.2007.04.015. PMID 17570575.
  4. ^ a b "Entrez Gene: MX1 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)".

Further reading[edit]